منابع مشابه
Progestin: Synthetic Progesterone
Progestin is a synthetic form of progesterone [4], a naturally occurring hormone [5], which plays an important role in the female reproductive cycle. During the 1950s two types of progestin [6] that were later used in birth control [7] pills were created, norethindrone [8] and norethynodrel [9]. In 1951 Carl Djerassi [10] developed norethindrone [8] at Syntex [11], SA Laboratories located in Me...
متن کاملProgestin therapy in endometriosis.
Progestins are synthetic compounds that mimic the effects of progesteron. For over 50 years, oral progestins have been demonstrated to be effective in the treatment of endometriosis. They were reported to reduce or eliminate pain symptoms in approximately 90% of the patients. Progestins are available in many forms, including oral preparations, injections, subdermal implants and intrauterine sys...
متن کاملCombination Estrogen–Progestin Oral Contraceptives
N Engl J Med 2003;349:1443-50. Copyright © 2003 Massachusetts Medical Society. A healthy, sexually active, 35-year-old woman presents for advice about the use of oral contraceptives. She does not smoke cigarettes and has no personal or family history of venous thromboembolism, myocardial infarction, or stroke. Her blood pressure is 120/80 mm Hg. Should an oral contraceptive be prescribed, and i...
متن کاملEffects of estrogen and estrogen-progestin on mammographic parenchymal density. Postmenopausal Estrogen/Progestin Interventions (PEPI) Investigators.
BACKGROUND In longitudinal studies, greater mammographic density is associated with an increased risk for breast cancer. OBJECTIVE To assess differences between placebo, estrogen, and three estrogen-progestin regimens on change in mammographic density. DESIGN Subset analysis of a 3-year, multicenter, double-blind, randomized, placebo-controlled trial. SETTING Seven ambulatory study center...
متن کاملProgestin therapy for endometrial cancer: the potential of fourth-generation progestin (review).
Progestin preparations are made of synthetic progesterone and have often been used for hormone therapy in gynecological patients with endometriosis or endometrial cancer. Hormone therapy using progestin is considered to be one of the effective means of treatment particularly when dealing with endometrial cancer (an estrogen-dependent tumor). Numer...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1934
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)75413-6